• "If we even managed to achieve a modest delay of five years in the manifestation of this disease, this could lead to a fifty per cent reduction in number of people affected" (K. Marek. 2005)

Alzheimer's disease begins many years before the onset of the first symptoms. This fact opens a window of opportunity because if we diagnose those affected during this pre-symptomatic stage and treat them with therapies aimed at stopping or slowing its progression, the impact of the disease would be very much reduced. If we achieve a 5-year delay at the beginning of the manifestation of the disease, there would be a fifty per cent reduction in the number of people affected. This is precisely the purpose pursued by the CITA-Alzheimer Foundation with the performance of the Gipuzkoa Alzheimer's project (PGA), its main line of research.

EThe ultimate objective is to anticipate the degeneration and implement preventive measures to avoid the development of symptoms or treatments that minimize it. It is the best strategy for the defeat of Alzheimer's disease. Thanks to the voluntary participation of 500 healthy people, we have created a research platform that we share with scientific groups from around the world, from Amsterdam to Washington, London to Philadelphia. The platform consists of a database of demographic, epidemiological, clinical and neuropsychological disorders, a bank of biological samples (blood and cerebrospinal fluid) and a file of structural and functional brain images obtained with a 3T RNM machine. This is an enormously valuable platform that will serve to define the pre-clinical and prodromal stage of the disease, which still remains an unresolved challenge. In this way, the CITA-Alzheimer Foundation will help to complete the puzzle involving the origin of Alzheimer's disease. This is science in capital letters, generated in Gipuzkoa and scattered all over the planet.


The Gipuzkoa Alzheimer's Project (PGA) has been made possible thanks to the participation of 500 volunteers.

These are 500 people who have taken a step forward for 500 reasons that inspire them to get involved. PGA research wishes to respond to these reasons and concerns. Thank you for your generosity and for not faltering in this long-distance race. Because this is "our" project. We continue counting on you.

Follow-up Committee

A Monitoring Committee has been established as a result of the progress made by the Gipuzkoa Alzheimer Project with the role of offering advice on decision-making in matters essential for the development of the research and that may be of general interest. Volunteers and researchers participate in this committee.


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