4. Memory and cholesterol, alterations in the brain network. Study of cerebral diffusivity as biomarker for the pre-clinical diagnosis of Alzheimer's disease in high-risk subjects.

Principal Researcher: Mª Teresa García Sebastián

Status: Ongoing.

Purpose: To research the presence of changes in the microstructure of the tracts of the white substance in participants from the Basque PGA study cohort with increased risk of AD through analysis of diffusion tensor imaging (DTI). To analyse the association between the inter-individual variability in the total cholesterol levels, HDL, LDL) and triglycerides in blood with the changes in the DTI.

Funding entity: SAIOTEK. Basque Government. Department of Industry, Innovation, Trade and Tourism. 2012-2013. Project no.: CA-2012-072

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