Letter from the scientific director

Facing Alzheimer’s disease requires a global, international and multidisciplinary approach. At Fundación CITA-alzheimer Fundazioa we are convinced that, together with a modern, efficacious, close and human clinical care work it is clinical research that will drive the necessary steps towards the defeat of Alzheimer’s disease.

Fundación CITA-alzheimer Fundazioa has based its Research activity on two directive ideas: to concentrate on the earliest stages of the disease process and the commitment of translating research results into actions made readily available to all citizens.

The multi-disciplinary team at the Memory Clinic of Fundación CITA-alzheimer Fundazioa consists of nurses, neurologists, neuropsychologists, neuroradiologists with wide experience. Advanced diagnostic procedures such as 3T MRI, cerebrospinal fluid biomarkers, and access to amyloid-PET are available at the Clinic.

In 2011 we kicked-off the Gipuzkoa Alzheimer Project (the GAP study), an innovative and pioneer longitudinal study on the pre-clinical stages to contribute to prevention. We are also doing research on the earliest symptomatic stages and promoting the development of methods and pathways to facilitate earlier detection and interventions. For this we set up the “STOP Alzheimer 2020/A shared challenge” project in 2015. This plan includes the Deba epidemiologic study (Deba Laboratory) and coordinates the efforts and resources of the Fundación, Osakidetza (the Public Health System), AFAGI (local Alzheimer’s Patients and Family Association), the local Town-Hall and citizens. Results from these two studies have already allowed initiating public-private early detection and intervention pilot programs.

Fundación CITA-alzheimer Fundazioa contributes to develop new anti-alzheimer drugs participating in clinical trials promoted by pharmaceutical and biotechnology companies. The aim is to make these trials available to all patients who may be so generously willing to contribute to the advance of medicine and science.

The scientific accuracy with which the Fundación CITA-alzheimer Fundazioa group tries to imbue its research activity has permitted to build up and make available to the whole scientific community a high quality research platform that gathers an enormous amount of data, biological samples (serum, plasma urine, CSF), and brain structural and functional images from more than 600 very well clinically and cognitively phenotyped persons. .

Fundación CITA-alzheimer Fundazioa collaborates with centers and institutions at local, National and international levels. The GAP study cohort has been included in large European projects such as the European Medical Initiatives Framework-Alzheimer’s Disease (EMIF-AD). Moreover, our center has been selected and certified as a Trial Delivering Center for the European Alzheimer’s Disease Prevention, EPAD project. We have put Gipuzkoa and Euskadi into the Alzheimer’s research world map.

All these efforts would have by no means been possible without the generosity and commitment of our volunteers and participants or without the support from competitive and non-competitive financial grants or donations we receive and keep seeking from public or private institutions and donors. To all them please allow me to express here our deepest and most sincere gratitude. Eskerrik asko denori!


Pablo Martinez-Lage

Scientific Director


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