Cita Alzheimerwww.cita-alzheimer.org

Publicaciones

Proyecto Gipuzkoa Alzheimer

Jon B Toledo, Henrik Zetterberg, Argonde C van Harten, Lidia Glodzik, Pablo Martinez-Lage, Luisella Bocchio, Lorena Rami, Oscar Hansson, Reisa Sperling, Sebastiaan Engelborghs, Hugo Vanderstichele, Manu Vandjick, Harald Hampel, Stefan Teipl, Marilyn Albert, William T Hu, Jose. A Monge Argilés, Peter De Deyn, Bradley T Hyman, Jose L. Molinuevo, Giovanni B. Frisoni, Gurutz Linazasoro, Ana Gorostidi, Mony de Leon, Wiesje M. van der Flier, Philip Scheltens, Leslie M Shaw, John Q Trojanowski. Alzheimer’s disease CSF biomarker levels in Cognitively Normal Subjects: Multicenter Study. Brain. 2015 Sep;138(Pt 9):2701-15.

Daniel Alcolea, Pablo Martínez-Lage, Pascual Sánchez-Juan, Javier Olazarán, Carmen Antúnez, Andrea Izagirre, Mirian Ecay-Torres, Ainara Estanga, Montserrat Clerigué, Mª Concepción Guisasola, Domingo Sánchez Ruiz, Juan Marín Muñoz, Miguel Calero, Rafael Blesa, Jordi Clarimón, María Carmona-Iragui, Estrella Morenas-Rodríguez, Eloy Rodríguez-Rodríguez, José Luis Vázquez Higuera, Juan Fortea, Alberto Lleó. Amyloid precursor protein metabolism and inflammation markers in preclinical Alzheimer Disease. Neurology 2015 Aug; 85(7):626-633

M. ten Kate, E.J. Sanz-Arigita, B.M. Tijms, A.M. Wink, M. Clerigue, M. Garcia-Sebastian, A. Izagirre, M. Ecay-Torres, A. Estanga, J. Villanua, H. Vrenken, P.J. Visser, P. Martinez-Lage, F. Barkhof. Impact of APOE-ɛ4 and family history of dementia on gray matter atrophy in cognitively healthy middle-aged adults. Neurobiology of Aging 2015

Betty Tijms, Mara ten Kate, Alle Meije Wink, Pieter Jelle Visser, Mirian Ecay, Montserrat Clerigue, Ainara Estanga, Maite Garcia Sebastian, Andrea Izaguirre, Jorge Villanua, Pablo Martinez Lage, Wiesje van der Flier, Philip Scheltens, Ernesto SanzArigita, Frederik Barkhof. Grey matter network disruptions and Alzheimer’s disease pathology in non-demented elderly. Neurobiology of Aging xxx (2015): 1-7

Otaegui-Arrazola A, Amiano P, Elbusto A, Urdaneta E, Martínez-Lage P. Diet, cognition and Alzheimer´s disease: Food for thought. Eur J Nutr, 2014; 53 (1): 1-23.

Alcolea D, Martinez-Lage P, Izagirre A, Clerigué M, Carmona-Iragui M, Alvarez RM, Fortea J, Balasa M, Morenas-Rodríguez E, Lladó A, Grau O, Blennow K, Lleó A, Molinuevo JL. Feasibility of lumbar puncture in the study of cerebrospinal fluid biomarkers for Alzheimer's disease: a multicenter study in Spain. J Alzheimers Dis. 2014; 39(4):719-26.

FH Duits, P Martinez-Lage, C Paquet, S Engelborghs, A Lleó, L Hausner, JL Molinuevo, E Stomrud, L Farotti, IHGB Ramakers, M Tsolaki, C Skarsgård, R Åstrand, A Wallin, M Vyhnalek, M Holmber-Clausen, OV Forlenza, L Ghezzi, M Ingelsson, EI Hoff, G Roks, A de Mendonça, JM Papma, A Izagirre, M Taga , H Struyfs, DA Alcolea, L Frölich, M Balasa, L Minthon, JWR Twisk, S Persson, H. Zetterberg, WM van der Flier, CE Teunissen, P Scheltens, K Blennow. Performance and complications of lumbar puncture in memory clinics: results of the multicenter LP feasibility study. 2014.Phonation Biomechanic Analysis of Alzheimer´s Disease Cases. Neurocomputing 05/2015; 167. DOI:10.1016/j.neucom.2015.03.087 JCR: 2.08

López-de-Ipiña K, Alonso JB, Solé-Casals J, Barroso N, Henríquez P , Faundez-Zanuy M, Travieso CM, Ecay-Torres M, Martínez-Lage P, Eguiraun H. On Automatic Diagnosis of Alzheimer’s Disease Based on Spontaneous Speech Analysis and Emotional Temperature. Cognitive Computation, 30 de Agosto 2013, online

López-de-Ipiña K, Alonso JB, Travieso CM, Solé-Casals J, Egiraun H, Faundez-Zanuy M, Ezeiza A, Barroso N, Ecay-Torres M, Martinez-Lage P, Martinez de Lizardui U. On the selection of non-invasive methods based on speech analysis oriented to automatic Alzheimer disease diagnosis. Sensors (Basel). 2013;21;13(5):6730-45.

 

Investigadores CITA-alzheimer

Bocchetta M, Galluzzi S, Kehoe PG, Aguera E, Bernabei R, Bullock R, Ceccaldi M, Dartigues JF, de Mendonça A, Didic M, Eriksdotter M, Félician O, Frölich L, Gertz HJ, Hallikainen M, Hasselbalch SG, Hausner L, Heuser I, Jessen F, Jones RW, Kurz A, Lawlor B, Lleo A, Martinez-Lage P, Mecocci P, Mehrabian S, Monsch A, Nobili F, Nordberg A, Rikkert MO, Orgogozo JM, Pasquier F, Peters O, Salmon E, Sánchez-Castellano C, Santana I, Sarazin M, Traykov L, Tsolaki M, Visser PJ, Wallin ÅK, Wilcock G, Wilkinson D, Wolf H, Yener G, Zekry D, Frisoni GB. The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey. Alzheimer`s Dement. 2015 Feb; 11(2):195-206.

Mar J, Soto-Gordoa M, Arrospide A, Moreno-Izco F, Martínez-Lage P. Fitting the epidemiology and neuropathology of the early stages of Alzheimer's disease to prevent dementia. Alzheimers Res Ther. 2015 Jan 15;7(1):2.

Arbizu J, García-Ribas G, Carrió I, Garrastachu P, Martínez-Lage P, Molinuevo JL. Recommendations for the use of PET imaging biomarkers in the diagnosis of neurodegenerative conditions associated with dementia: SEMNIM and SEN consensus. Rev Esp Med Nucl Imagen Mol. 2015 Sep-Oct;34(5):303-13.

Bergareche A, Rodriguez-Oroz MC, Estanga A, Gorostidi A, Lopez de Munain A, Castillo-Triviño T, Ruiz-Martínez J, Mondragón E, Gaig C, Lomeña F, Sarasqueta C, Tolosa E, Marti-Masso JF. DaTSCAN and Clinical biomarkers in relatives at genetic risk for LRRK2 R1441G Parkinson’s disease. Mov Disord Journal 2015

Gasca-Salas C, Estanga A, Clavero P, Aguilar-Palacio I, González-Redondo R, Obeso JA, Rodríguez-Oroz MC. Longitudinal assessment of the pattern of cognitive decline in non-demented patients with advanced Parkinson's disease. J Parkinsons Dis. 2014;4(4):677-86.

Estanga A, Rodriguez-Oroz MC, Ruiz-Martinez J, Barandiaran M, Gorostidi A, Bergareche A, Mondragon E, Lopez de Munain A, Marti-Masso JF. Cognitive dysfunction in Parkinson's disease related to the R1441G mutation in LRRK2. Parkinsonism Relat Disord. 2014 Oct;20(10):1097-100.

Ruiz-Martínez J, de la Riva P, Rodríguez-Oroz MC, Mondragón Rezola E, Bergareche A, Gorostidi A, Gago B, Estanga A, Larrañaga N, Sarasqueta C, López de Munain A, Martí Massó JF. Prevalence of cancer in Parkinson's disease related to R1441G and G2019S mutations in LRRK2. Mov Disord. 2014 May;29(6):750-5.

Villanua Bernues J* and Sanz-Arigita EJ*. Plataforma de imagen en un instituto de investigacion: el papel del radiologo. Accepted for publication. Actualizaciones SERAM -edición 2014; capítulo 3a. *Shared co-authorship.

Arbizu J, Prieto E, Martinez-Lage P, Martí-Climent JM, García-Granero M, Lamet I, Pastor P, Riverol M, Gómez-Isla MT, Peñuelas I, Richter JA, Weiner MW; Alzheimer's Disease Neuroimaging Initiative. Automated analysis of FDG PET as a tool for single-subject probabilistic prediction and detection of Alzheimer's disease dementia. Eur J Nucl Med Mol Imaging. 2013; 40(9):1394-405.

Bocchetta M, Galluzzi S, Kehoe PG, Aguera E, Bernabei R, Bullock R, Ceccaldi M, Dartigues JF, de Mendonça A, Didic M, Eriksdotter M, Félician O, Frölich L, Gertz HJ, Hallikainen M, Hasselbalch SG, Hausner L, Heuser I, Jessen F, Jones RW, Kurz A, Lawlor B, Lleo A, Martinez-Lage P, Mecocci P, Mehrabian S, Monsch A, Nobili F, Nordberg A, Rikkert MO, Orgogozo JM, Pasquier F, Peters O, Salmon E, Sánchez-Castellano C, Santana I, Sarazin M, Traykov L, Tsolaki M, Visser PJ, Wallin ÅK, Wilcock G, Wilkinson D, Wolf H, Yener G, Zekry D, Frisoni GB. The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey. Alzheimers Dement. 2015 Feb;11(2):195-206.

Mar J, Soto-Gordoa M, Arrospide A, Moreno-Izco F, Martínez-Lage P. Fitting the epidemiology and neuropathology of the early stages of Alzheimer's disease to prevent dementia. Alzheimers Res Ther. 2015 Jan 15;7(1):2.

Moreno F, Sala-Llonch R, Barandiarán M, Sánchez-Valle R, Estanga A, Bartrés-Faz D, Sistiaga A, Alzualde A, Fernández E, Martí Massó JF, López de Munain A, Indakoetxea B.

Gasca-Salas C, Estanga A, Clavero P, Aguilar-Palacio I, González-Redondo R, Obeso JA, Rodríguez-Oroz MC. Longitudinal assessment of the pattern of cognitive decline in non-demented patients with advanced Parkinson's disease. J Parkinsons Dis. 2014;4(4):677-86. Neurobiol Aging. 2013; 34(5):1462-8.

Estanga A, Rodriguez-Oroz MC, Ruiz-Martinez J, Barandiaran M, Gorostidi A, Bergareche A, Mondragon E, Lopez de Munain A, Marti-Masso JF. Cognitive dysfunction in Parkinson's disease related to the R1441G mutation in LRRK2. Parkinsonism Relat Disord. 2014 Oct;20(10):1097-100.

Ruiz-Martínez J, de la Riva P, Rodríguez-Oroz MC, Mondragón Rezola E, Bergareche A, Gorostidi A, Gago B, Estanga A, Larrañaga N, Sarasqueta C, López de Munain A, Martí Massó JF. Prevalence of cancer in Parkinson's disease related to R1441G and G2019S mutations in LRRK2. Mov Disord. 2014 May;29(6):750-5.

Moreno F, Sala-Llonch R, Barandiaran M, Sánchez-Valle R, Estanga A, Bartrés-Faz D, Sistiaga A, Alzualde A, Fernández E, Martí Massó JF, López de Munain A, Indakoetxea B. Distinctive age-related temporal cortical thinning in asymptomatic granulin gene mutation carriers. Neurobiol Aging. 2013 May;34(5):1462-8.

Barandiaran M, Estanga A, Moreno F, Indakoetxea B, Alzualde A, Balluerka N, Martí Massó JF, López de Munain A. Neuropsychological features of asymptomatic c.709-1G>A progranulin mutation carriers. J Int Neuropsychol Soc. 2012 Nov;18(6):1086-90.

Moreno F, Indakoetxea B, Barandiaran M, Alzualde A, Gabilondo A, Estanga A, Ruiz J, Ruibal M, Bergareche A, Martí-Massó JF, López de Munain A. "Frontotemporoparietal" dementia: clinical phenotype associated with the c.709-1G>A PGRN mutation. Neurology. 2009 Oct 27;73(17):1367-74.

Pérez-Grijalba V, Pesini P, Monleón I, Boada M, Tárraga L, Ruiz-Laza A, Martinez-Lage P, San-José I, Sarasa M. Several direct and calculated biomarkers from the amyloid-β pool in blood are associated with an increased likelihood of suffering from mild cognitive impairment. J Alzheimers Dis. 2013; 1; 36(1):211-9.

Rodríguez-Rodríguez E, Sánchez-Juan P, Vázquez-Higuera JL, Mateo I, Pozueta A, Berciano J, Cervantes S, Alcolea D, Martinez-Lage P, Clarimón J, Lleó A, Pastor P, Combarros O. Genetic risk score predicting accelerated progression from mild cognitive impairment to Alzheimer's disease. J Neural Transm. 2013; 120(5):807-12.

Sanz-Arigita EJ y García Sebastián MT. Marcadores de imagen: estructura, función y conectividad cerebral. (2012) Book 200 Años de ConstiTAUción y “Viva la PePa”. Estimular el ingenio, reserve cognitiva y Alzheimer (XVII Curso Nacional de Enfermedad de Alzheimer). Enfoque Editorial SC. Chapter 13:172-186

Pesini P, Pérez-Grijalba V, Monleón I, Boada M, Tárraga L, Martínez-Lage P, San-José I, Sarasa M. Reliable Measurements of the β-Amyloid Pool in Blood Could Help in the Early Diagnosis of AD. Int J Alzheimers Dis. 2012; 604141.

Vellas B, Hausner L, Frölich L, Cantet C, Gardette V, Reynish E, Gillette S, Agüera-Morales E, Auriacombe S, Boada M, Bullock R, Byrne J, Camus V, Cherubini A, Eriksdotter-Jönhagen M, Frisoni GB, Hasselbalch S, Jones RW, Martinez-Lage P, Rikkert MO, Tsolaki M, Ousset PJ, Pasquier F, Ribera-Casado JM, Rigaud AS, Robert P, Rodriguez G, Salmon E, Salva A, Scheltens P, Schneider A, Sinclair A, Spiru L, Touchon J, Zekry D, Winblad B, Andrieu S. Progression of Alzheimer disease in Europe: data from the European ICTUS study. Curr Alzheimer Res. 2012; 8:902-12.

Boada M, Antunez C, López-Arrieta J, Caruz A, Moreno-Rey C, Ramírez-Lorca R, Morón FJ, Hernández I, Mauleón A, Rosende-Roca M, Martínez-Lage P, Marín J, Tárraga L, Alegret M, Pedrajas JR, Urda N, Royo JL, Saez ME, Gayán J, González-Pérez A, Real LM, Ruiz A, Galán JJ. Estrogen receptor alpha gene variants are associated with Alzheimer's disease. Neurobiol Aging. 2012; 33(1):198,15-24.

Martinez-Lage P, Pepp M. Alzheimer's disease and its treatment with a novel transdermal patch therapy: survey of caregiver experiences. Prim Care Companion CNS Disord. 2012;14(4).

González-Redondo R, Toledo J, Clavero P, Lamet I, García-García D, García-Eulate R, Martínez-Lage P, Rodríguez-Oroz MC. The impact of silent vascular brain burden in cognitive impairment in Parkinson's disease. Eur J Neurol. 2012 Aug;19(8):1100-7

Sanz-Arigita EJ y García Sebastián MT. Marcadores de imagen: estructura, función y conectividad cerebral. (2011) Book Alzheimer 2011. Prevencion, Alzheimer, Mediterraneo: crisol de disciplinas. (XVI Curso Nacional de Enfermedad de Alzheimer). Enfoque Editorial SC. Chapter 15:237-252

Savio A, Garcia Sebastian MT, Chyzhyk D, Hernández C, Graña M, Sistiaga A, López de Munain A, Villanua J. Neurocognitive disorder detection based on Feature Vectors extracted from VBM analysis of structural MRI. Computers in Biology and Medicine 2011; 41:600¬610

Graña M, Chyzhyk D, García Sebastián MT, Hernández C. Lattice Independent Component Analysis for functional Magnetic Resonance Imaging. Information Sciences 2011; 181:1910¬1928.

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